Treatment Result of Postoperative Radiotherapy of Carcinoma of the Uterine Cervix.
- Author:
Charn Il PARK
1
;
Jung Soo KIM
;
Il Han KIM
;
Sung Whan HA
;
Hyo Pyo LEE
;
Myon Woo SHIN
Author Information
1. Department of Therapeutic Radiology, College of Medicine, Seoul National University, Korea.
- Publication Type:Original Article
- Keywords:
Carcinoma of the uterine cervix;
Postoperative radiotherapy;
Actuaral survival;
Failure rate;
Complication
- MeSH:
Cervix Uteri*;
Cystitis;
Disease-Free Survival;
Female;
Humans;
Intestinal Obstruction;
Lymph Nodes;
Neoplasm Metastasis;
Radiation Oncology;
Radiotherapy*;
Recurrence;
Seoul;
Survival Rate
- From:Journal of the Korean Society for Therapeutic Radiology
1985;3(2):103-112
- CountryRepublic of Korea
- Language:English
-
Abstract:
The early carcinoma of the uterine cervix may be treated by either radical surgery or radical radiotherapy according to the patient's characteristics, and the survival is high with either treatment. But, because of the size of the lesion, metastasis to lymph nodes, and vascular space invasion by tumor have all been shown to influence recurrence and survival, postoperative radiotherapy may be considered as their histopathologic finding after radical surgery. However, there are still debates on the increasing survival rates with postoperative radiotherapy. Two hundreds and three patients with carcinoma of the uterine cervix who were treated with postoperative radiotherapy from February 1979 to September 1982 in the Department of Therapeutic Radiology, Seoul National University were analyzed and following results were obtained. 3-ear actuarial survival rate and 3-ear disease free survival rate were 83.4% and 73.4% respectively and 3-ear actuarial survival rates by stages were 90.7% for IB, 69.6% for IIA, and 85.2% for IIb. 3-ear actuarial free survival rates by stage IB, IIA, IIB were 79.8%, 67.8%, 68.3% respectively. The overall failure rate was 25.1%(51/203); local recurrence rate was 8.4%, distant metastasis rate was 14.3% and simultaneous local recurrence and distant metastasis was 2.4%. Failure rates by stages were 19.8%(18/19) for IB, 29.1%(16/55) for IIA and 29.8%(17/57) for IIB. The overall acute complication rate was 57.6%; tolerable cases was 50.2% and severe cases was 7.4%, Late complication rate was 7.9% and the major late complication were intestinal obstruction, aggravated urinary symptom, radiation cystitis in order of frequency.
