Glaucoma Discrimination by Combined Use of Frequency Doubling Technology and Heidelberg Retina Tomography II.
- Author:
Ho RA
1
;
Chan Kee PARK
Author Information
1. Department of Ophthalmology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. ckpark@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Frequency doubling technology;
Heidelberg retina tomography
- MeSH:
Classification;
Discrimination (Psychology)*;
Glaucoma*;
Humans;
Retina*;
ROC Curve;
Sensitivity and Specificity
- From:Journal of the Korean Ophthalmological Society
2005;46(2):306-315
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study investigated whether the combined use of Frequency Doubling Technology and Heidelberg Retina Tomography II increases the usefulness of glaucoma detection. METHODS: The study subjects were, 59 patients with POAG and 34 normal persons were selected. The authors defined a total of six discriminative criteria: F1, in which the conventional analysis of FDT was used; F2, in which the FDT scoring system was used; F3, in which the Moorfield classification of HRT was used; F4, in which the new HRT discrimination function `Z' was used; F5, in which F1 and F3 were combined, and F6, in which F2 and F4 were combined; The usefulness of each criterion was investigated. RESULTS: The sensitivity, specificity, and area under the ROC curve of the six discriminative criteria were: 86.4%, 58.8%, and 0.740 in F1, 4.5%, 80.0% (cutoff: 12.50), and 0.882 in F2, 79.7%, 61.8%, and 0.679 in F3, 77.6%, 74.3% (cutoff: 0), and 0.857 in F4, 77.6%, 71.4% (cutoff: 1.0805), and 0.767 in F5, and 86.2%, 91.4% (cutoff: 0.495) and 0.931 in F6. CONCLUSIONS: Combined use of functional (FDT) and morphological (HRT) aspects, which are early parameters of glaucoma damage, gave more useful results than a single analysis of each. Thererfore, the combined use will help the early detection of glaucoma.
