Xanthogranulomatous Inflammation Presenting as a Submucosal Mass of the Stomach.
- Author:
Min Kyoung PARK
1
;
Hong Jun YANG
;
Chang Hoon LIM
;
Tae Ho KIM
;
Chang Whan KIM
;
Jean A KIM
;
Wook KIM
;
Sok Won HAN
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. kimchmd@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Xanthogranulomatous inflammation;
Stomach submucosal mass;
Colonic involvement
- MeSH:
Colon;
Colon, Transverse;
Gallbladder;
Gallstones;
Gastrointestinal Tract;
Humans;
Inflammation;
Kidney;
Macrophages;
Stomach
- From:Korean Journal of Gastrointestinal Endoscopy
2009;38(5):284-287
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Xanthogranulomatous inflammation is a rare chronic inflammatory condition that is characterized by aggregation of lipid-laden foamy macrophages (xanthoma cells). Although the precise pathogenesis of xanthogranulomatous inflammation is not well understood, various mechanisms have been proposed, including chronic recurrent infection, the presence of gallstones, immunologic disorders and defective lipid transport. This disease entity is well recognized in the kidney and gallbladder, yet involvement of the gastrointestinal tract is extremely rare and the involvement of both the stomach and colon has never been reported on. A coexisting malignancy rarely has been reported in a patient with xanthogranulomatous inflammation. This might present as an inflammatory mass-like lesion with infiltration to the surrounding tissues, and so this often mimics advanced cancer. Therefore, a surgical operation together with careful pathological evaluation is required for making the precise diagnosis. We herein report on a case of xanthogranulomatous inflammation that presented as a submucosal mass in the stomach which was a huge irregular mass involving transverse colon.
