A Case of Primary Biliary Cirrhosis in Association with Sjorgen's Syndrome Developing Features of Systemic Lupus Erythematosus.
- Author:
Chang Gyo LEE
1
;
Hyun Kyu CHANG
;
Seung Yong KIM
;
Ho Hyung KANG
;
Duk Jae KIM
;
Chin Kun CHANG
;
Ju Hi MAENG
;
Hui Sup LEE
;
Pae Gun PARK
;
Jae Gul CHUNG
Author Information
1. Department of Internal Medicine, Ulsan University, Asan-Kangnung Hospital, Kangnung, Korea. hanks@knh.co.kr
- Publication Type:Case Report
- Keywords:
Primary biliary cirrhosis;
Sjorgen's Syndrome;
Systemic lupus erythematosus
- MeSH:
Bile;
Classification;
Female;
Humans;
Liver Cirrhosis, Biliary*;
Lupus Erythematosus, Systemic*;
Middle Aged;
Sjogren's Syndrome
- From:The Journal of the Korean Rheumatism Association
2001;8(1):59-63
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary biliary cirrhosis (PBC)is a chronic inflammatory disease characterized by fibrous obliteration of intrahepatic bile ductules.Although the etiopathogenesis of PBC remains unclear,several studies suggest that a disordered immune response may be involved.This disease is commonly associated with various autoimmune diseases,such as Sjogren's syndrome,scleroderma, rheumatoid arthritis,Hashimoto's thyroiditis,polymyositis,and pernicious anemia.More than 80%of cases with PBC are accompanied by at least one autoimmune disorder,and 40%by two or more. Sjogren's syndrome,defined by dry eyes and xerostomia,may be found in 69 to 81%of PBC patients. However, concurrent coexistence of PBC and systemic lupus erythematosus (SLE)has been rarely described in the literature.We report a 46-year-old female with PBC and Sjogren's syndrome who also satisfied a classification criteria of SLE.
