Primary Cutaneous Anaplastic Large Cell Lymphoma of the Lower Lid.
- Author:
Mi Rang KIM
1
;
Jun Young CHI
;
Young Hyeh KO
;
Yoon Duck KIM
Author Information
1. Department of Ophthalmology, Samsung Medical Center School of Medicine, Sungkyunkwan University, Seoul, Korea. ydkim@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Cutaneous anaplastic large cell lymphoma;
Eyelid tumor;
Inflammatory lesion
- MeSH:
Adult;
Biopsy;
Cell Membrane;
Cytoplasm;
Dermis;
Diagnosis;
Extremities;
Eyelids;
Humans;
Lymphoma, Primary Cutaneous Anaplastic Large Cell*;
Triamcinolone;
Ulcer
- From:Journal of the Korean Ophthalmological Society
2005;46(12):2086-2090
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Primary cutaneous anaplastic large cell lymphoma is rarely encountered in the lower eyelids. We report a patient with primary cutaneous anaplastic large cell lymphoma arising from the lower eyelid. METHODS: A 39-year-old man presented with a relatively fast growing mass on the center of his left lower eyelid for one month. The mass did not respond to local injection of triamcinolone at a local clinic. The lesion appeared as a solitary reddish nodule with ulceration, was non-tender, round, crusted, and measured 13 mm x 11 mm x 5 mm. Well- developed superficial vessels were found on the surface of the nodule. An incisional biopsy was performed. RESULTS: Histologic examination revealed that the bulk of the infiltrate was in the papillary and reticular dermis. Tumor cells had abundant, well-defined cytoplasm and pleomorphic nuclei with multiple nucleoli. The majority of the neoplastic cells showed immunoreactivity for CD 30 (Ki-1) along the cell membrane. A histopathological diagnosis of primary cutaneous anaplastic large cell lymphoma was made. CONCLUSIONS: Most cases of primary cutaneous anaplastic large cell lymphoma arise from the body and extremities. However, since primary cutaneous anaplastic large cell lymphoma may occur in the eyelid, it should be differentiated from nodular and relatively fast growing inflammatory tumors despite local steroid treatment.
