A case of orbital Polyarteritis Nodosa Complicated with Retinal Vasculitis and Exophthalmos.
- Author:
Hyun Gue KIM
1
;
Su Hyung LEE
;
In Taek KIM
Author Information
1. Department of Ophthalmology, Ulsan Dong-Kang Hospital, Korea.
- Publication Type:Original Article
- Keywords:
Exophthalmos;
Polyarteritis nodosa;
Retinal vasculitis
- MeSH:
Anophthalmos;
Arteries;
Biopsy;
Cornea;
Corneal Ulcer;
Ethmoid Bone;
Exophthalmos*;
Exudates and Transudates;
Female;
Humans;
Middle Aged;
Muscles;
Nasal Cavity;
Nasal Septum;
Orbit*;
Peptic Ulcer;
Polyarteritis Nodosa*;
Retinal Hemorrhage;
Retinal Vasculitis*;
Retinaldehyde*;
Tomography, X-Ray Computed;
Vasculitis
- From:Journal of the Korean Ophthalmological Society
2003;44(1):215-219
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Polyarteritis nodosa is a necrotizing vasculitis affecting medium and small sized arteries throughout the vascular system, including ocular tissues. We report a case of orbital polyarteritis nodosa complicated with retinal vasculitis and exophthalmos. METHODS: A 51-year-old woman complained of swelling and hard mass in periorbital region for 3 months. The left eye was anophthalmos after enucleation secondary to corneal infection. The patient has treated marginal ulcer of the cornea and keratomalacia. Posterior synechia and motility disturbance of lateral rectus muscle were also revealed. Fundus examination showed focal retinal hemorrhage, macular hard exudate, and soft exudate, which may mean retinal vasculitis. Both eyes gradually developed exophthalmos. Orbital CT scan revealed homogenous infiltration in the orbit, ethmoid bone, and nasal cavity and perforation of the nasal septum. The pathologic examination for the biopsy specimen from the orbital tissue demonstrated a nongranulomatous vasculitis, diagnosing the polyarteritis nodosa. RESULTS: The authors present ocular manifestations, including marginal corneal ulcer, keratomalacia, dysfunction of the extraocular muscles, posterior synechia, retinal hemorrhage, soft exudate, hard exdate in the macula, and exophthalmos, in this patient with the polyarteritis nodosa.
