Alpha-Fetoprotein-Producing Carcinoma of the Gallbladder: A case report.
- Author:
Seung Chul HEO
1
;
Kyu Hee HER
;
Sun Whe KIM
;
Hanseong KIM
;
Woo Ho KIM
;
Young Hyun PARK
Author Information
1. Department of Surgery, Seoul National University College of Medicine.
- Publication Type:Case Report
- Keywords:
Gallbladder carcinoma;
Alpha-fetoprotein
- MeSH:
Adenocarcinoma;
alpha-Fetoproteins;
Cholecystectomy;
Cytoplasm;
Dyspepsia;
Fetal Proteins;
Follow-Up Studies;
Gallbladder*;
Humans;
Liver;
Neoplasm Metastasis;
Tomography, X-Ray Computed
- From:Journal of the Korean Surgical Society
1999;57(1):149-156
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We experienced a case of a gallbladder carcinoma detected incidentally by elevated serum alpha- fetoprotein. The patient had a symptom of mild intermittent indigestion, and a routine medical examination revealed elevation of serum alpha-fetoprotein. A mass, 4 cm 3 cm, was located in the gallbladder and it had not infiltrated the liver. The serum level of alpha-fetoprotein decreased after a cholecystectomy. The gallbladder mass was an adenocarcinoma of hepatoid differentiation. Cytoplasms of the tumor cells had positive reactivity to immunohistochemical staining of alpha-fetoprotein. In the course of postoperative follow up, the serum alpha-fetoprotein level increased continuously, and abdominal CT scanning proved multiple intrahepatic metastases.
