Multiple intestinal lymphomatous polyposis in a Jindo dog.
- Author:
Da Hee JEONG
1
;
Sun Hee DO
;
Il Hwa HONG
;
Hai Jie YANG
;
Dong Wei YUAN
;
Dong Hag CHOI
;
Kyu Shik JEONG
Author Information
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords: B-cells; canine; CD20; multiple intestinal lymphoma; lymphomatous polyposis
- MeSH: Animals; Antigens, CD20/metabolism; Dog Diseases/*pathology/surgery; Dogs; Immunohistochemistry/veterinary; Intestinal Neoplasms/pathology/surgery/*veterinary; Intestinal Polyps/*pathology/surgery; Lymphoma, Mantle-Cell/pathology/surgery/*veterinary; Male
- From:Journal of Veterinary Science 2006;7(4):401-403
- CountryRepublic of Korea
- Language:English
- Abstract: A male, 5-year-old Jindo dog underwent enterectomy and enteroanastomosis due to ileus of the intestine at a local veterinary hospital. Grossly, the excised intestine showed markedly thickened multinodular masses in the serosal layer of the upper part, and soft-to-firm, creamcolored neoplastic masses that displayed extensive nodular mucosal protuberances into the lumen. The neoplastic masses were filled with large round cells that were ovoid in shape and they had pale and/or hyperchromatic nuclei. The neoplastic cells had mainly infiltrated into the mucosal and submucosal layers, and they had diffusely invaded the muscular and serosal layers. Therefore, the diagnosis of canine multiple intestinal malignant lymphomatous polyposis was made based on the gross and histopathological findings. The origin of these tumor cells was determined to be B-cells since they were positive for anti-CD20.
