The Clinical Study of Clarithromycin for the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
10.12701/yujm.1997.14.1.94
- Author:
Ki Beom KIM
1
;
Chang Jin SHIN
;
Hak Jun LEE
;
Jin Hong CHUNG
;
Kwan Ho LEE
;
Hyun Woo LEE
Author Information
1. Department of Internal Medicine College of Medicine, Yeungnam University Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Clarithromycin;
Chronic;
obstructive pulmonary disease
- From:Yeungnam University Journal of Medicine
1997;14(1):94-100
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To evaluate the efficacy and safety of clarithromycin in acute exacerbation of chronic obstructive pulmonary disease, we administered clarithromycin(250mg) twice in a day in 30 patients with acute exacerbation of chronic obstructive pulmonary disease from September to November in 1996. Twenty eight eases of 30 patients were cured(93.4%) and 2 cases(6.7%) show clinical improvement. Three cases were improved within 3 days of treatment and 24 cases were improved between 5 days and 12 days of treatment. There were no significant side effects. These results suggest that clarithromycin will be effective as a first line therapy in patients with acute exacerbation of chronic obstructive pulmonary disease.
