Comparision of Single Versus Split-dose of Polyethylene Glycol-electrolyte Solution for Colonoscopy Preparation.
- Author:
Sang Hoon KIM
1
;
Dong Il PARK
;
Seung Ha PARK
;
Hong Joo KIM
;
Yong Kyun CHO
;
In Kyung SUNG
;
Chong Il SOHN
;
Woo Kyu JEON
;
Byung Ik KIM
Author Information
1. Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. diksmc.park@samsung.com
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Colonoscopy;
Bowel preparation;
Ottawa scale;
Polyethylene glycol solution
- MeSH:
Colonoscopy*;
Compliance;
Eating;
Humans;
Intubation;
Outpatients;
Polyethylene*;
Residual Volume
- From:Korean Journal of Gastrointestinal Endoscopy
2005;30(4):194-198
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Although polyethethylene glycol (PEG) solution is widely used for bowel preparation, it is difficult to drink a large amount of fluid in a short period of time. We compared the quality of bowel preparation and compliance between the single-dose group and split-dose group. METHODS: Two hundred seventeen patients undergoing outpatient colonoscopy were randomly assigned to receive either 4 litre (L) of PEG solution (n=104, single-dose group) on the day of colonoscopy or 2 L of PEG solution on the day before colonoscopy and then 2 L of same solution on the day of colonoscopy (n=113, split-dose group). The quality of bowel preparation was assessed using Ottawa scale. Cecal intubation time, compliance and side effects were assessed. RESULTS: Split-dose group showed the better quality of bowel preparation than single-dose group (4.75+/-2.45 vs 5.52+/-2.24, p <0.05) because of lower residual volume scale. Patients who experienced very difficulty during ingestion (0.95% vs 5.8%) and left out more than 25% of PEG solution (3.5% vs 8.7%) were greater in single-dose group. There was no difference of side effects between two groups. CONCLUSIONS: Split-dose PEG preparation could be the useful method in than single-dose in colonoscopy preparation.