Effect of Cryotherapy on Proliferative Vitreoretinopathy(PVR).
- Author:
Hum CHUNG
1
;
Jeong Min HWANG
Author Information
1. Department of Ophthalmology, College of Medicine, Seoul National University, Korea.
- Publication Type:Original Article
- Keywords:
proliferative vitreoretinopathy(PVR);
cryotherapy;
retinal tear;
retinal pigment epithelial(RPE) cell
- MeSH:
Cryotherapy*;
Diathermy;
Epiretinal Membrane;
Humans;
Retinal Perforations;
Retinaldehyde
- From:Journal of the Korean Ophthalmological Society
1989;30(1):87-91
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cryotherapy is blamed for inducing or aggravating PVR, by releasing retinal pigment epithelial(RPE) cells. These are based on the fact that PVR rarely occurs in non-operated eye, and many of PVR patients have received cryotherapy during surgery. Nontheless, in eyes with diathermy also developed PVR, and although there have been many experiments, the effect of cryotherapy on inducing PVR was not proven experimentally in the living eye. We made retinal tears in the living rabbit eyes, and applied cryotherapy on one eye of each rabbit. The result was compared histopathologically with noncryothermized control eye. There was no statistically significant difference between the two groups concerning the migration of RPE, and the proliferation of RPE. Although the formation of epiretinal membrane was more obvious in the cryothermized group, the difference was not statistically significant.