Extra-gastric MALT lymphoma: Analysis of 50 cases.
- Author:
Sung Yong OH
1
;
Won Seog KIM
;
Ji Hyang KIM
;
Seo Yonug SONG
;
Ki Hyun KIM
;
Eun Mi NAM
;
Young Hae KOH
;
Howe J REE
;
Yoon Duck KIM
;
Yong Chan AHN
;
Won Gi KANG
;
Sung Soo YOON
;
Hong Gi LEE
;
Chan Hyun PARK
;
Keun Chil PARK
Author Information
1. Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Lymphoma;
Mucosa - associated lymphoid tissue
- MeSH:
Bone Marrow;
Conjunctiva;
Female;
Follow-Up Studies;
Humans;
Lung;
Lymphoma;
Lymphoma, B-Cell, Marginal Zone*;
Male;
Medical Records;
Prognosis;
Recurrence;
Retrospective Studies;
Survival Rate
- From:Korean Journal of Medicine
2000;59(3):261-267
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Mucosa-associated lymphoid tissue(MALT) lymphoma has an indolent natural course. However, extra-gastric MALT lymphoma has been reported to have more frequent relapses and shorter time to progress than gastric MALT lymphoma. We performed this study to analyze clinical features of extra-gastric MALT lymphoma. METHODS: We retrospectively reviewed the medical records of the patients who were diagnosed as extra-gastric MALT lymphoma at the Samsung Medical Center from March 1995 to January 1999. The survival was analyzed by Kaplan-Meier method. RESULTS: During the study period, extra-gastric MALT lymphoma was diagnosed in 50 patients. The median age was 51(28-87)yaers. The male to female ratio was 22:28. Commonly involved sites were conjunctiva (25/50, 50%), lung (6/50, 12%) and intestine(6/50, 12%). Histopathologically, low to high grade ratio of extra-gastric MALT lymphoma was 47:3. Among 41 patients who were staged, 32 patients(78%) had stage I or II and 9 patients(22%)had stage IV. B symptoms were seen in only 3 patients. Bone marrow involvement was observed in 4 patients. The duration of median follow up was 22 months. The 1-year and 2-year survival rates were 95.1% and 91.4% retrospectively. CONCLUSION: Majoity of our cases with extra-gastric MALT lymphoma had low grade, early stage, good treatement reponse and good prognosis.
