The in vitro effects of methamidophos on oxygen uptake, carbonic production
- Author:
Anh Tuan Bui
- Publication Type:Journal Article
- Keywords:
methamidophos
- MeSH:
methamidophos;
In Vitro
- From:Journal of Medical Research
1999;9(1):19-23
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
(MAP) on O2 uptake, CO2 production and rate of methemoglobin of human erythrocytes. The in vitro effects of methamidophos (MAP) on O2 uptake, CO2 production and rate of methemoglolin of human erythrocytes were studied: (1) after exposure of human erythrocytes to MAP at the concentrations from 1 to 10mM, only at concentration higher than 100mM of MAP in 37oC for 3 hours, the hemolysis was significantly induced. (2) at MAP concentrations between 1 and 10 mM, the significant increase of oxygen uptake and carbonic productions in human erythrocytes was seen. (3) At MAP concentrations between 1 and 10 mM, rate of methemoglobin in erythrocytes was increased significantly. These findings suggest that MAP act as oxidative chemical
