Lymphomatoid Papulosis Presenting a Single Nodule.
10.5021/ad.1996.8.3.232
- Author:
Ji Hyeung CHO
;
Jae Hong KIM
;
Chan Kum PARK
- Publication Type:Case Report
- Keywords:
Lymphomatoid papulosis;
A single nodular eruption;
CD30(Ki-1) positive large cell lymphoma
- MeSH:
Biopsy;
Chronic Disease;
Diagnosis, Differential;
Eosinophils;
Humans;
Lymphocytes;
Lymphoma;
Lymphomatoid Papulosis*;
Middle Aged;
Neutrophils;
Numismatics;
Recurrence;
Thigh
- From:Annals of Dermatology
1996;8(3):232-236
- CountryRepublic of Korea
- Language:English
-
Abstract:
Lymphomatoid papulosis is a chronic disease of cutaneous atypical lymphoid infiltration characterized clinically by involuting and recurring papules, plaques, and sometimes nodules. A 51-year-old man presented with a single, coin sized, nontender, erythematous nodule on the left thigh of a 2-week duration. There was a history of recurrence and spontaneous healing of similar asymptomatic eruptions five to six times over 20 years. A biopsy specimen showed a dense, wedge-shaped dermal infiltrate that was patchy and perivascular. The cellular infiltrate was polymorphous and consisted of large atypical cells, small lymphocytes, eosinophils and neutrophils. The large atypical cells were strongly CD30(Ki-1) positive. We report a case of lymphomatoid papulosis unusually presenting as a single nodular eruption, in which the differential diagnosis between lymphomatoid papulosis and CD30(Ki-1)positive large cell lymphoma is exceedingly difficult.
