Usefulness of Magnifying Chromoscopy in Ulcerative Colitis.
- Author:
Jung Woo SHIN
1
;
Chang Young LIM
;
You Sik CHOI
Author Information
1. Department of Internal Medicine, Research Institute for Gastroenterology, Dankook University College of Medicine, Cheonan, Korea.
- Publication Type:Original Article
- Keywords:
Magnifying chromoscopy;
Ulcerative colitis
- MeSH:
Colitis;
Colitis, Ulcerative*;
Colon;
Colonoscopy;
Diagnosis;
Dysentery, Amebic;
Humans;
Indigo Carmine;
Inflammatory Bowel Diseases;
Mucous Membrane;
Pathology;
Ulcer*
- From:Korean Journal of Gastrointestinal Endoscopy
2001;22(1):21-26
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Ulcerative colitis is an inflammatory bowel disease with unknown etiology, which has waxed and waned course. It is diagnosed by colon study, pathology, and especially colonoscopy. It is difficult to differentiate between ulcerative colitis and other infectious colitis, especially amebic colitis, and to confirm of remnant lesion by endoscopic findings. METHODS: Magnifying colonoscopy has 100 time magnifying power compared to 30 time of conventional colonoscopy. By spraying 0.2% indigo carmine dye, we evaluated the magnifying and microscopic findings of 31 colonic mucosa of 23 patients with ulcerative colitis. RESULTS: Initial and magnifying chromoscopic findings in ulcerative colitis were loss of cryptal opening 72% (13/18), loss of submucosal vessel 89% (16/18), mucosal denudation (or microscopic erosion) 83% (15/18), and mucosal unevenness 94% (17/18). Recovery rate of magnifying chromoscopic findings after treatment in ulcerative colitis were in crytal opening 80% (8/10), submucosal vascularity 60% (6/10), mucosal denudation (microscopic erosion) 30% (3/10), and in mucosal unevenness 40% (4/10). CONCLUSIONS: It is suggested that magnifying chromoscopic findings in ulcerative colitis may be useful in initial diagnosis and confirmation of remnant lesion, but, not in prediction of clinical severity.
