Delayed Diagnosis of Falciparum Malaria with Acute Kidney Injury.
10.3346/jkms.2016.31.9.1499
- Author:
Iee Ho CHOI
1
;
Pyoung Han HWANG
;
Sam Im CHOI
;
Dae Yeol LEE
;
Min Sun KIM
Author Information
1. Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea. children@jbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Plasmodium falciparum;
Malaria;
Diagnosis;
Renal Failure;
Dialysis, Plasmapheresis
- MeSH:
Acute Kidney Injury*;
Adolescent;
Africa;
Anemia, Hemolytic;
Antimalarials;
Delayed Diagnosis*;
Diagnosis;
Diarrhea;
Disseminated Intravascular Coagulation;
Dysuria;
Early Diagnosis;
Fever;
Headache;
Hematuria;
Humans;
Hyperbilirubinemia;
Kenya;
Malaria*;
Male;
Nigeria;
Plasmapheresis;
Plasmodium falciparum;
Pyuria;
Renal Dialysis;
Renal Insufficiency;
Thrombocytopenia;
Urinalysis
- From:Journal of Korean Medical Science
2016;31(9):1499-1502
- CountryRepublic of Korea
- Language:English
-
Abstract:
Prompt malaria diagnosis is crucial so antimalarial drugs and supportive care can then be rapidly initiated. A 15-year-old boy who had traveled to Africa (South Africa, Kenya, and Nigeria between January 3 and 25, 2011) presented with fever persisting over 5 days, headache, diarrhea, and dysuria, approximately 17 days after his return from the journey. Urinalysis showed pyuria and hematuria. Blood examination showed hemolytic anemia, thrombocytopenia, disseminated intravascular coagulation, and hyperbilirubinemia. Plasmapheresis and hemodialysis were performed for 19 hospital days. Falciparum malaria was then confirmed by peripheral blood smear, and antimalarial medications were initiated. The patient's condition and laboratory results were quickly normalized. We report a case of severe acute renal failure associated with delayed diagnosis of falciparum malaria, and primary use of supportive treatment rather than antimalarial medicine. The present case suggests that early diagnosis and treatment is important because untreated tropical malaria can be associated with severe acute renal failure and fatality. Physicians must be alert for correct diagnosis and proper management of imported tropical malaria when patients have travel history of endemic areas.
