Systemic lupus erythematosus accompanied with idiopathic inflammatory myopathy: report of 2 cases.
- Author:
Young Ah PARK
1
;
Seung Ho SONG
;
Dong Woo KIM
;
Jung Hyuk KIM
;
Hyun Kyu CHANG
;
Jee Young LEE
;
Na Hye MYONG
Author Information
1. Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea. hanks22@dankook.ac.kr
- Publication Type:Case Report
- Keywords:
Lupus Erythematosus;
Systemic;
Dermatomyositis;
Polymyositis
- MeSH:
Adult;
Autoantibodies;
Dermatomyositis;
DNA;
Exanthema;
Female;
Humans;
Lupus Erythematosus, Systemic*;
Muscles;
Myalgia;
Myositis*;
Polymyositis
- From:Korean Journal of Medicine
2003;65(5):604-609
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Generalized myalgia and muscle tenderness are relatively common during exacerbations in patients with systemic lupus erythematosus (lupus), and inflammatory myositis involving the proximal muscles occurs in 5~11% of patients during the course of the disease. However, patients with overlap syndrome of lupus and idiopathic inflammatory myopathy have been not that frequent. We described 2 patients with overlap syndrome of these two diseases. Patient 1 was a 27-year-old female patient concurrently having lupus and dermatomyositis. She manifested the characteristic skin rash for dermatomyositis such as heliotrope rash. Patient 2 was a 32-year-old female patient concurrently having lupus and polymyositis, in whom the disease-specific autoantibodies for lupus or idiopathic inflammatory myopathy such as anti-ds DNA antibody, anti-Sm antibody and anti-Jo-1 antibody were positive.
