A case of toxic hepatitis caused by the chinese diet food.
- Author:
Dong Soo LEE
1
;
Jong Tae BAEK
;
Jun Seok KIM
;
Sun Jong JEUNG
;
Hye Kyung LEE
;
Byung Min AHN
;
Ki Hwa YANG
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. hepatotoxicity@empal.com
- Publication Type:Case Report
- Keywords:
Chinese diet food, Fenfluramine;
Hepatitis toxic;
RUCAM, M and V scale
- MeSH:
Adult;
Asian Continental Ancestry Group*;
China;
Diet*;
Drug-Induced Liver Injury*;
Eating;
Female;
Fenfluramine;
Humans;
Japan;
Korea;
Liver;
Malaysia;
Pathology;
Singapore;
Weight Loss
- From:Korean Journal of Medicine
2003;65(Suppl 3):S689-S692
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Recently over 500 victims with toxic hepatitis associated with some sort of Chinese diet food for weight reduction were developed in Japan, China, Singapore and Malaysia. These Chinese goods contain several kinds of Chinese herbs and fenfluramine, the well known anti-appetite drug. However, until today, it is not determined which component of the diet food is responsible for the hepatic injury. Nowadays, toxic hepatitis is frequently seen in daily practice, second only to viral origin in Korea. We present a 38-year-old woman who developed mixed cholestatic and hepatocellular injury after 5 week's ingestion of the Chinese diet food. The causality of this agent to the hepatotoxicity was assessed by RUCAM and M and V scale. Herein we described the clinical course and liver pathology of this patient.
