Bilateral Acute Retinal Necrosis Syndrome in the Patient with Acquired Immunodeficiency Syndrome.
- Author:
Sang Jin KIM
1
;
Hyeong Gon YU
Author Information
1. Department of Ophthalmology, Seoul National University College of Medicine, Korea.
- Publication Type:Case Report
- Keywords:
Acute retinal necrosis (ARN);
AIDS;
Ganciclovir
- MeSH:
Acquired Immunodeficiency Syndrome*;
Acyclovir;
Anterior Chamber;
Diagnosis, Differential;
Ganciclovir;
Humans;
Middle Aged;
Necrosis;
Retinal Detachment;
Retinal Necrosis Syndrome, Acute*;
Retinaldehyde;
Retinitis;
Syphilis;
Vasculitis;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2003;44(10):2445-2450
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report one case of bilateral acute retinal necrosis (ARN) syndrome in the patient with acquired immunodeficiency syndrome (AIDS). METHODS: Bilateral retinal necrosis, occlusive vasculitis, vitreous opacity and inflammatory reaction in anterior chamber were noted in a 48-years old man with AIDS. RESULTS: The patient was diagnosed as bilateral ARN, but did not respond to intravenous acyclovir therapy. However, the patient was successfully treated with intravenous ganciclovir at a dosage of 5 mg/kg/day, which resulted in resolution of retinal lesion and improvement of visual acuity without complications such as retinal detachment. CONCLUSIONS: CMV retinitis, progressive outer retinal necrosis, ocular syphilis should be considered in the differential diagnosis of ARN syndrome in the AIDS patients and alternative treatment with ganciclovir should be considered promptly when the patient do not respond to acyclovir therapy.
