Recurrent Stent Thrombosis in a Patient with Antiphospholipid Syndrome and Dual Anti-Platelet Therapy Non-Responsiveness.
- Author:
You Hong LEE
1
;
Hyoung Mo YANG
;
Seung Jea TAHK
;
You Sun HONG
;
Jin Sun PARK
;
Kyoung Woo SEO
;
Yong Woo CHOI
;
Choong Kyun NOH
Author Information
- Publication Type:Case Report
- Keywords: Antiphospholipid syndrome; Percutaneous coronary intervention; Stents; Thrombosis
- MeSH: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome*; Causality; Coronary Artery Bypass; Coronary Artery Disease; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Stents*; Thrombosis*
- From:Korean Circulation Journal 2015;45(1):71-76
- CountryRepublic of Korea
- Language:English
- Abstract: Antiphospholipid syndrome (APS), the most common acquired hypercoagulable condition, is diagnosed by persistent presence of antiphospholipid antibodies and episodes of vascular thrombosis. It may be an important predisposing factor for stent thrombosis, resulting in poor outcomes. Also, anti-platelet therapy non-responsiveness is associated with stent thrombosis. We report a case of a 39-year-old man who after undergoing successful percutaneous coronary intervention for significant coronary artery disease suffered repeated stent thrombosis events leading to ST-segment elevation myocardial infarction. Eventually, he underwent coronary artery bypass surgery because of uncontrolled thrombosis and was diagnosed as having APS and dual antiplatelet therapy non-responsiveness.
