Case Characteristics, Hyperacute Treatment, and Outcome Information from the Clinical Research Center for Stroke-Fifth Division Registry in South Korea.
- Author:
Beom Joon KIM
1
;
Jong Moo PARK
;
Kyusik KANG
;
Soo Joo LEE
;
Youngchai KO
;
Jae Guk KIM
;
Jae Kwan CHA
;
Dae Hyun KIM
;
Hyun Wook NAH
;
Moon Ku HAN
;
Tai Hwan PARK
;
Sang Soon PARK
;
Kyung Bok LEE
;
Jun LEE
;
Keun Sik HONG
;
Yong Jin CHO
;
Byung Chul LEE
;
Kyung Ho YU
;
Mi Sun OH
;
Dong Eog KIM
;
Wi Sun RYU
;
Ki Hyun CHO
;
Joon Tae KIM
;
Jay Chol CHOI
;
Wook Joo KIM
;
Dong Ick SHIN
;
Min Ju YEO
;
Sung Il SOHN
;
Jeong Ho HONG
;
Juneyoung LEE
;
Ji Sung LEE
;
Byung Woo YOON
;
Hee Joon BAE
Author Information
- Publication Type:Multicenter Study ; Review
- Keywords: Stroke registry; South Korea; Case profile; Hyperacute treatment; Thrombolysis; Outcome; Recurrent event
- MeSH: Asian Continental Ancestry Group; Humans; Korea; Length of Stay; Male; National Institutes of Health (U.S.); Stroke; Tissue Plasminogen Activator
- From:Journal of Stroke 2015;17(1):38-53
- CountryRepublic of Korea
- Language:English
- Abstract: Characteristics of stroke cases, acute stroke care, and outcomes after stroke differ according to geographical and cultural background. To provide epidemiological and clinical data on stroke care in South Korea, we analyzed a prospective multicenter clinical stroke registry, the Clinical Research Center for Stroke-Fifth Division (CRCS-5). Patients were 58% male with a mean age of 67.2+/-12.9 years and median National Institutes of Health Stroke Scale score of 3 [1-8] points. Over the 6 years of operation, temporal trends were documented including increasing utilization of recanalization treatment with shorter onset-to-arrival delay and decremental length of stay. Acute recanalization treatment was performed in 12.7% of cases with endovascular treatment utilized in 36%, but the proportion of endovascular recanalization varied across centers. Door-to-IV alteplase delay had a median of 45 [33-68] min. The rate of symptomatic hemorrhagic transformation (HT) was 7%, and that of any HT was 27% among recanalization-treated cases. Early neurological deterioration occurred in 15% of cases and were associated with longer length of stay and poorer 3-month outcomes. The proportion of mRS scores of 0-1 was 42% on discharge, 50% at 3 months, and 55% at 1 year after the index stroke. Recurrent stroke up to 1 year occurred in 4.5% of patients; the rate was higher among older individuals and those with neurologically severe deficits. The above findings will be compared with other Asian and US registry data in this article.
