Primary Intraosseus Xanthoma Involving the Proximal Femur in a Normolipidemic Patient: A Case Report.

Author: Won Chul SHIN ¹ ; Nam Hoon MOON ; Kuen Tak SUH
Author Information

1. Department of Orthopaedic Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Korea.
Publication Type:Case Report
Keywords: Primary intraosseous xanthoma; Normolipidemic; Proximal femur
MeSH: Adult; Bone Transplantation; Chylomicrons; Curettage; Female; Femur*; Follow-Up Studies; Hip; Humans; Lipoma; Lipoproteins; Recurrence; Reference Values; Xanthomatosis*
From:Hip & Pelvis 2016;28(3):182-186
CountryRepublic of Korea
Language:English
Abstract: We report the case of a 25-year-old woman presenting with left hip pain. A lesion was found in the proximal femoral metaphysis. Benign bone tumor, such as intraosseous lipoma or liposclerosing myxofibrous tumor, was suspected based on simple radiographs and magnetic resonance images. Curettage of the lesion and bone grafting was performed. Histologic findings reflected primary intraosseous xanthoma of the proximal femur. Laboratory tests revealed the patient to be normolipidemic, while immunoelectrophoretic fractionation of lipoproteins revealed normal values for alpha, pre-beta, beta, and chylomicrons. At the one-year follow-up, there was no evidence of local recurrence. This is the first reported case of primary intraosseous xanthoma of the proximal femur in a normolipidemic patient.