The Effect on IVF-ET Outcomes of Intramural Myomas.
- Author:
Ae Hyun LEE
1
;
Byeong Yun KIM
;
Gun Oh CHONG
;
Kee Sang PARK
;
Sung Yob KIM
;
Taek Hoo LEE
;
Sang Sik CHUN
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Kyungpook National University, Korea.
- Publication Type:Original Article
- Keywords:
Intramural myoma;
Infertility;
IVF-ET
- MeSH:
Gyeongsangbuk-do;
Gynecology;
Humans;
Infertility;
Leiomyoma;
Myoma*;
Obstetrics;
Pregnancy Rate
- From:Korean Journal of Obstetrics and Gynecology
2004;47(5):957-965
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The aim of this study was to assess the effect of intramural uterine myoma in patients with a normal endometrial cavity on IVF-ET cycle outcome. This study was also investigated to find out whether medical supression or myomectomy needs to precede to IVF-ET. METHODS: The subjects were 300 infertile patients who got IVF-ET from January 1999 to December 2002 at the Department of Obstetrics and Gynecology in Kyungpook National University Hospital, and they were divided into myoma group of 97 patients and non-myoma group of 203 ones. This study group did not include patients found to have large myoma (>or= 7 cm), or myoma distorting the uterine cavity. RESULTS: Compared with the results of IVF-ET according to the presence of intramural uterine myoma, pregnancy rate and implantation rate between two groups had no statistically significant differences (p>0.05). Further comparisons within the myoma group showed no difference in pregnancy rate by number of myomas or site of myomas (p>0.05). CONCLUSION: Intramural uterine myoma not distorting the uterine cavity is considered to have no effect on the outcome of IVF-ET and no difference in the pregnancy rate according to the number of myomas or site of myomas. Therefore, these findings suggest that medical treatments or myomectomy before IVF-ET is not necessary to those infertile patients with intramural uterine myomas not distorting the uterine cavity.