Comparative Study of Vecurnium and Domestic Product of Vecaron in Human.
10.4097/kjae.1990.23.4.515
- Author:
Woo Jong SHIN
1
;
Hwan Yeong CHOI
;
Jong Hoon YEOM
;
Dong Whan KIM
;
Jong Hun JUN
;
Khung Hun KIM
;
Dong Ho LEE
;
Kyo Sang KIM
;
Jung Kook SUH
;
Hee Koo YOO
;
Ik Sang SEUNG
;
Se Ung CHON
Author Information
1. Department of Anesthesiology, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Comparative Study ; Original Article
- Keywords:
Muscle relaxant-domestic vecaron;
Vecuronium
- MeSH:
Anesthesia;
Blood Pressure;
Cholinesterase Inhibitors;
Depression;
Heart Rate;
Humans*;
Intubation;
Muscle Relaxation;
Vecuronium Bromide
- From:Korean Journal of Anesthesiology
1990;23(4):515-519
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The introduction of musele relaxants was an epoch-making event in the development of clinical anesthesia and their use has hecome essential to anesthesia practice. Vecuronium, one of the newest muscle relaxant, has many advantages; it is rapid and short-acting, noncumulative, has minimal side reactions and is promptly antagonized by anticholinesterases was introduced recently our clinical anesthesia practice. Fortunately, domestic product of vecuronium as vecaron was introduced lately. Therefore, this study was performed to evaluate the effects of vecaron and as compare with vecuronium. The results were as follows: 1) Similar effects of muscle relaxation was observed in both group except the onset time of twitch depression was shorter in vecuronium group than vecaron group. 2) Blood pressure and heart rate was increased during intubation in groups. 3) Recovery index was slightly prolonged in vecuronium group than vecaron group but no significance was observed. However, this recovery index of vecuronium was slightly shorter than previous observations.
