Wilm`s Tumor: Prognosis and Treatment.
- Author:
Kyung Seop LEE
1
;
Sung Choon LEE
Author Information
1. Keimyung University, School of Medicine, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Wilm`s tumor;
stage;
prognosis;
histology
- MeSH:
Anesthesia;
Child;
Child, Preschool;
Diagnosis;
Drug Therapy;
Humans;
Prognosis*;
Survival Rate
- From:Korean Journal of Urology
1987;28(6):763-768
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Wilms` tumor originates from pleuripotential mesenchymal cells of the metanephrogenic blastema. Improvement on surgery and anesthesia, addition of radiation therapy and chemotherapy have produced remarkable improvements in survival over the past several decades. Twenty-eight patients with histologically confirmed diagnoses of Wilms` tumor were treated from l972 through l987 at the University Hospital, Keimyung University School of Medicine. l. Two year survival rate according to tumor stage was 80% in stage I, 7516 in stage II , 57.1% in stage III and 25% in stage IV and the overall 2 year survival rate was 57.1 1K . 2. Two year survival rate according to age was 75% in below l year, 50% between l to 2 years old, 54.5% between 2 to 6 years old and 60% above 6 years old. However, there seems to be no close relationship between age and prognosis. 3. Two year survival rate before 1978 was 45.5% and after 1978 was 45.5% and after 1978 it was 61.6% 4. There was 76.0 percent overall survival for those with negative nodes versus 33.3 per cent survival for those with positive nodes. 5. Two year survival rates of FH(Favorable Histology) and UH(Unfavorable Histology) were 68.2% and 16.7% respectively. There seems to be close relationship between FH and UH.
