Surgical Treatment of Langerhans Cell Histiocytosis in the Rib: Two cases report.
- Author:
Yang haeng LEE
1
;
Do kyun KANG
;
Jae min PARK
;
Il Yong HAN
;
Hee jae JUN
;
Young chul YOON
;
Yun ho HWANG
;
Kwang hyun CHO
Author Information
1. Department of Thoracic & Cardiovascular Surgery, Pusan Paik Hospital, College of Medicine, Inje University. cstlee@ijnc.inje.ac.kr
- Publication Type:Case Report
- Keywords:
Histiocytosis;
Ribs;
Rib neoplasm
- MeSH:
Eosinophilic Granuloma;
Femur;
Histiocytosis;
Histiocytosis, Langerhans-Cell*;
Humans;
Natural History;
Ribs*;
Skull;
Skull Base
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2005;38(11):799-802
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Langerhans cell histiocytosis (LCH) involves disorders previously referred as "histiocytosis X" (including eosinophilic granuloma, Letterer-Siwe, and Hand-Schuller syndrome). Its clinical patterns are various and it is a basically benign tumoral condition but with a strong tendency toward dissemination and destruction. Its natural history is unpredictable. But, in solitary bone lesion, wide resection with tumor-free margin is required in order to provide the best chance for a cure. In the majority of patients LCH is a osteolytic lesion with a predilection for calvarium and is rarely seen in the skull base and the femur. LCH of rib, especially if solitary, is relatively rare. We report two rare cases of solitary LCH developed in the rib, which were successfully treated by surgical resection.
