The prevalence of microalbuminuria and associated factors in newly diagnosed type 2 diabetes mellitus in Korea.
- Author:
Dong Jin KIM
1
;
Seong Jin RYU
;
Young Jin SEO
;
Nam Hoon KIM
;
Hye Soo CHUNG
;
Chai Ryoung EUN
;
Hye Jung CHOI
;
Hye Sook KIM
;
Sae Jeong YANG
;
Juri PARK
;
Hye Jin YOO
;
Soo Yeon PARK
;
Yun Jeong LEE
;
Ohk Hyun RYU
;
Kye Won LEE
;
Hee Young KIM
;
Ji A SEO
;
Sin Gon KIM
;
Nan Hee KIM
;
Kyung Mook CHOI
;
Sei Hyun BAIK
;
Dong Seop CHOI
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. cdongs@kumc.or.kr
- Publication Type:Original Article
- Keywords:
Microalbuminuria;
Prevalence;
Diabetes mellitus;
type 2;
Metabolic syndrome
- MeSH:
Academic Medical Centers;
Body Mass Index;
C-Peptide;
Creatinine;
Diabetes Mellitus;
Diabetes Mellitus, Type 2*;
Fasting;
Humans;
Insulin;
Korea*;
Prevalence*;
Proteinuria;
Triglycerides
- From:Korean Journal of Medicine
2007;73(5):503-511
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: To determine the prevalence and the associated factors of microalbuminuria in Korean subjects with newly diagnosed type 2 diabetes mellitus. METHODS: A total of 304 patients with newly diagnosed type 2 diabetes mellitus that visited Anam Hospital, Korea University Medical Center, were studied cross-sectionally for the presence of microalbuminuria and other micro- and macrovascular complications. Microalbuminuria was calculated by the amount of albumin excretion in the urine for 24 hrs (30-299 mg/24hr) or by the albumin creatinine ratio in a spot urine sample (30-299 mg/g creatinine). Subjects were divided into two groups: the normoalbuminuria group and the microalbuminuria group. RESULTS: The prevalence of microalbuminuria, normoalbuminuria and overt proteinuria in patients with newly diagnosed type 2 diabetes mellitus was 17.1%, 80.3% and 2.6%. respectively. Microalbuminuria was significantly correlated with the body mass index (BMI), fasting insulin level, fasting C-peptide level and triglyceride level. The number of metabolic syndrome components was significantly correlated with the amount of microalbuminuria. In patients with microalbuminuria and without retinopathy, the correlation of microalbuminuria and the presence of metabolic syndrome was also significant. CONCLUSIONS: The prevalence of microalbuminuria in 304 Korean patients with newly diagnosed type 2 diabetes mellitus was 17.1%, and microalbuminuria had a correlation with the BMI, fasting insulin level, fasting C-peptide level, HOMA level, triglyceride level and the presence of metabolic syndrome.
