A Case of Mild Hemolytic Disease of the Fetus and Newborn - The First Case of Anti-Di(b) Identified on Prescreening Test during Pregnancy -.
- Author:
Ji Won CHOI
1
;
Moon Jung KIM
;
Myung Han KIM
;
Jung Ran PARK
;
Hyun Ok KIM
Author Information
1. Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea. hyunok1019@yuhs.ac
- Publication Type:Case Report
- Keywords:
Anti-Di(b);
Hemolytic disease of a fetus and newborn;
Antenatal screening
- MeSH:
Coombs Test;
Fetus;
Humans;
Infant;
Infant, Newborn;
Mass Screening;
Mothers;
Phenotype;
Phototherapy;
Pregnancy;
Prenatal Care;
Prenatal Diagnosis
- From:Korean Journal of Blood Transfusion
2010;21(2):165-170
- CountryRepublic of Korea
- Language:English
-
Abstract:
The Di(a+b-) phenotype is extremely rare among Caucacians and mostly confined to mongoloids. The clinical significance of anti-Di(b) is incompletely recognized. The authors report here a mild case of hemolytic disease of the fetus and newborn (HDFN) due to anti-Di(b). The mother was Di(a+b-) with anti-Di(b), which was detected by antenatal screening. She delivered a Di(a+b+) infant with a positive direct antiglobulin test and mild hemolytic disease. The infant was treated by phototherapy and subsequently recovered without the need for exchange transfusion. We suggest that the screening program as routine prenatal care is necessary.
