Anti-Ok(a) Antibody: The First Case Report in Korea.
- Author:
Hyoeun SHIM
1
;
Hyun Jun PARK
;
Chun Sung LEE
;
Seog Woon KWON
Author Information
1. Department of Laboratory Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea. swkwon@amc.seoul.kr
- Publication Type:In Vitro ; Case Report
- Keywords:
Anti-Ok(a) antibody;
Antibody screening test;
High-incidence antigen
- MeSH:
Blood Group Incompatibility;
Female;
Fetus;
Humans;
Infant, Newborn;
Korea;
Middle Aged;
Scoliosis;
Ursidae
- From:Korean Journal of Blood Transfusion
2010;21(2):171-174
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anti-Ok(a) was detected in a 56-year-old female patient who was admitted for surgical treatment of degenerative scoliosis. Because Oka is a high-incidence antigen, anti-Ok(a) antibody is extremely rare. No case of hemolytic transfusion reaction or hemolytic disease of the fetus and newborn caused by anti-Ok(a) antibody has been reported so far, however, it is likely that anti-Ok(a) is clinically significant based on several in vivo and in vitro studies. When a patient who is bearing anti-Ok(a) needs transfusion of RBCs, transfusion of autologous blood or Ok(a-) RBCs from family members is recommended.
