Pulp response of beagle dog to direct pulp capping materials: Histological study.
10.5395/JKACD.2010.35.1.005
- Author:
Ji Hyun BAE
1
;
Young Gyun KIM
;
Pil Young YOON
;
Byeong Hoon CHO
;
Yong Hoon CHOI
Author Information
1. Department of Conservative Dentistry, Seoul National University Bundang Hospital, Korea. yhchoi@snubh.org
- Publication Type:Original Article
- Keywords:
Direct pulp capping;
Pulp inflammation;
Dentinal bridge;
Histological evaluation;
Beagle dog
- MeSH:
Adhesives;
Aluminum Compounds;
Animals;
Calcium;
Calcium Compounds;
Calcium Hydroxide;
Composite Resins;
Dental Pulp Capping;
Dentin;
Dogs;
Drug Combinations;
Glutamates;
Guanine;
Hydroxides;
Jordan;
Minerals;
Necrosis;
Oxides;
Polymethyl Methacrylate;
Resin Cements;
Silicates;
Tooth;
Pemetrexed
- From:Journal of Korean Academy of Conservative Dentistry
2010;35(1):5-12
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study was to evaluate the pulp tissue reaction to direct pulp capping of mechanically exposed beagle dogs'pulp with several capping materials. A total of 36 teeth of 2 healthy beagle dongs were used. The mechanically exposed pulps were capped with one of the followings: (1) Mineral Trioxide Aggregate (MTA: ProRoot(R) MTA, Dentsply, Tulsa, USA), (2) Clearfil SE Bond (Dentin adhesive system: Kuraray, Osaka, Japan), (3) Ultra-Blend (Photo-polymerized Calcium hydroxide: Ultradent, South Jordan, USA), (4) Dycal (Quick setting Calcium hydroxide: LD Caulk Co., Milford, USA) at 7, 30, and 90 days before sacrificing. The cavities were restored with Z350 flowable composite resin (3M ESPE, St. Paul. MN, USA). After the beagle dogs were sacrificed, the extracted teeth were fixed, decalcified, prepared for histological examination and stained with HE stain. The pulpal tissue responses to direct pulp capping materials were assessed. In MTA, calcium hydroxide, and photo-polymerized calcium hydroxide groups, initial mild inflammatory cell infiltration, newly formed odontoblast-like cell layer and hard tissue bridge formation were observed. Compared with dentin adhesive system, these materials were biocompatible and good for pulp tissue regeneration. In dentin adhesive system group, severe inflammatory cell infiltration, pulp tissue degeneration and pulp tissue necrosis were observed. It seemed evident that application of dentin adhesive system in direct pulp capping of beagle dog teeth cannot lead to acceptable repair of the pulp tissue with dentine bridge formation.
