Heart Failure Secondary to Pazopanib for Treatment of Metastatic Renal Cell Carcinoma.
10.3904/kjm.2016.90.4.330
- Author:
Song I LEE
1
;
Byung Hun LIM
;
Young Jun KIM
;
Sang Woo KANG
;
Chull PARK
;
Joo Heung SONG
;
Seon Ho AHN
Author Information
1. Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea. ashneph@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
Pazopanib;
Carcinoma, Renal cell;
Heart failure
- MeSH:
Aged;
Carcinoma, Renal Cell*;
Digoxin;
Diuretics;
Dyspnea;
Follow-Up Studies;
Heart Failure*;
Heart Ventricles;
Heart*;
Humans;
Nephrectomy;
Oxygen;
Pleural Effusion;
Pulmonary Edema;
Thorax
- From:Korean Journal of Medicine
2016;90(4):330-333
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 78-year-old man was diagnosed with renal cell carcinoma, and left nephrectomy was performed. He started pazopanib. One month later, he visited our hospital because of general weakness and dyspnea. His oxygen saturation was low. A chest X-ray showed pulmonary edema and bilateral pleural effusion. An echocardiogram showed a larger left ventricle and lower ejection fraction than observed at the previous examination. The patient discontinued pazopanib and started diuretics and digoxin. His symptoms improved and a follow-up X-ray showed improvement in the pulmonary edema with bilateral pleural effusion.