Healthcare-associated Endocarditis by PVL-negative ST 72 SCCmec Type IV MRSA.
10.3904/kjm.2016.90.4.361
- Author:
Hye Mi OH
1
;
Kyung Up KIM
;
So Yeon PARK
;
Jin Seo LEE
;
Jae Seok KIM
;
Joong Sik EOM
Author Information
1. Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. helppl@hallym.ac.kr
- Publication Type:Case Report
- Keywords:
Methicillin-resistant staphylococcus aureus;
Endocarditis;
Linezolid
- MeSH:
Cerebral Hemorrhage;
Clone Cells;
Endocarditis*;
Genotype;
Humans;
Humerus;
Korea;
Methicillin-Resistant Staphylococcus aureus*;
Prevalence;
Thrombocytopenia;
Vancomycin;
Linezolid
- From:Korean Journal of Medicine
2016;90(4):361-364
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The prevalence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been increasing worldwide. In Korea, the most common genotype of CA-MRSA is the Panton-Valentine leukocidin-negative, sequence type 72 Staphylococcal cassette chromosome (SCC) mec type IV clone. However, within Korean hospitals, this strain is still not commonly reported. In this study, we describe a case of infective endocarditis caused by Panton-Valentine leukocidin-negative MRSA (ST72-SCCmec type IV A clone). Infection occurred after open reduction and internal fixation due to a right humerus fracture with cerebral hemorrhage. Initially, the patient was treated with linezolid, but with the onset of severe thrombocytopenia, the patient was switched to vancomycin therapy.
