Efficacy of Positron Emission Tomography/Computed Tomography in Gastric Mucosa-associated Lymphoid Tissue Lymphoma.
10.4166/kjg.2016.67.4.183
- Author:
Jin Won HWANG
1
;
Sam Ryong JEE
;
Sang Heon LEE
;
Ji Hyun KIM
;
Sang Yong SEOL
;
Seok Mo LEE
Author Information
1. Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. srjee@inje.ac.kr
- Publication Type:Original Article
- Keywords:
Positron emission tomography;
Stomach;
Lymphoma, B-cell, marginal zone
- MeSH:
Aged;
Female;
Fluorodeoxyglucose F18/chemistry/metabolism;
Gastroscopy;
Humans;
Lymphoma, B-Cell, Marginal Zone/*diagnosis/diagnostic imaging;
Male;
Middle Aged;
Positron Emission Tomography Computed Tomography;
Retrospective Studies;
Stomach Neoplasms/diagnostic imaging/metabolism
- From:The Korean Journal of Gastroenterology
2016;67(4):183-188
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: This study evaluated the diagnostic efficacy of fluorine-18 fluorodeoxyglucose PET/CT (F-18 FDG PET/CT) for patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma and examined the association between FDG avidity and the clinical factors affecting lesions. METHODS: Among the patients diagnosed with gastric MALT lymphoma, 16 who underwent a PET/CT for gastric MALT lymphoma were semi-quantitatively and qualitatively tested for FDG avidity of lesions in the stomach. Retrospectively collected data was analyzed to investigate the clinicoradiological factors and endoscopic findings between the patients with positive F-18 FDG PET/CT scans and those with negative scans. RESULTS: Eight of the 16 patients showed FDG avidity. When comparing the size of lesions in the stomach, the patients with FDG avidity had significantly larger lesions than those without (28.8 mm vs. 15.0 mm, p=0.03). The FDG-avid group has a significantly higher rate of positive CT scans than the non-avid group (75% vs. 13%, p=0.03). According to the endoscopic finding of the lesions, FDG avidity was pronounced with 75% of the protruding tumors, and 100% of the erosive-ulcerative types, which are a type of depressed tumors. CONCLUSIONS: When gastric MALT lymphoma is large, when lesions are found using abdominal CT scans, and the macroscopic appearance of a lesion is that of a protruding tumor or erosive-ulcerative type of depressed tumor, there is a high probability that such patients may have a positive F-18 FDG PET/CT scan.
