A Case of Mixed Small and Large Cell Neuroendocrine Carcinoma of the Uterine Cervix.
- Author:
Aeli RYU
1
;
Seong Taek MUN
;
Shi Sun KIM
Author Information
1. Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. sternum@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Uterine cervical neoplasms;
Neuroendocrine carcinoma;
Small cell carcinoma cervix;
Large cell neuroendocrine carcinoma
- MeSH:
Adult;
Biopsy;
Carcinoma, Neuroendocrine*;
Cervix Uteri*;
Combined Modality Therapy;
Disease Progression;
Female;
Humans;
Hysterectomy;
Lymph Node Excision;
Lymph Nodes;
Neoplasm Metastasis;
Prognosis;
Recurrence;
Uterine Cervical Neoplasms
- From:Soonchunhyang Medical Science
2014;20(2):108-111
- CountryRepublic of Korea
- Language:English
-
Abstract:
A rare case of mixed carcinoma of the cervix is reported, composed of a small and large cell neuroendocrine carcinoma. Neuroendocrine cervical carcinomas are very rare and aggressive. The prognosis is very poor despite multimodal treatment. Earlier reports have shown that the majority of patients present with advanced stage disease, have lymph node metastasis, and are at a high risk for recurrence and disease progression. In this study, we report the case of a 26-year-old woman with composite small and large cell neuroendocrine carcinoma of the cervix. A woman presented with vaginal bleed since 2 months of presentation. Gynecologic examination revealed cervical enlargement, and punch biopsy of the cervical lesion was performed. The biopsy was disclosed a large cell neuroendocrine carcinoma. The patient underwent a radical hysterectomy with bilateral salpingo-oophorectomy and pelvic lymph node dissection. The final histopathologic findings are mixed small and large cell neuroendocrine carcinoma of cervix.
