Overlap Syndrome with Features of Actue and Chronic Cutaneous Graft-versus-host Disease.
- Author:
Minseok CHEON
1
;
Young Bok LEE
;
Jung Eun KIM
;
Baik Kee CHO
;
Hyun Jeong PARK
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. hjpark@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Graft-versus-host disease;
Overlap syndrome;
Stem cell transplantation
- MeSH:
Consensus;
Graft vs Host Disease;
Humans;
Male;
National Institutes of Health (U.S.);
Peripheral Blood Stem Cell Transplantation;
Stem Cell Transplantation;
Transplants
- From:Korean Journal of Dermatology
2011;49(2):198-201
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Graft-versus-host disease (GVHD) has been divided into acute GVHD and chronic GVHD on the basis of 100 days post-transplantation. Recently, the National Institutes of Health in the USA proposed new consensus criteria for chronic GVHD; 1) classic chronic GVHD, presenting with diagnostic features of only chronic GVHD without characteristics of acute GVHD and 2) an overlap syndrome in which there are distinctive manifestations of chronic GVHD together with features of acute GVHD, irrespective of the period after transplantation. Herein we report a case of overlap syndrome that developed in a 15 year-old male who had undergone unrelated peripheral blood stem cell transplantation 4 years earlier.