Late-onset Systemic Lupus Erythematosus with Protein-losing Enteropathy, Vitiligo, and Diffuse Alveolar Hemorrhage.
10.12771/emj.2015.38.3.121
- Author:
Masashi OHE
1
;
Risshi KUDOH
;
Masahide SEKI
;
Motohiro ENDO
;
Mirei SHIKI
Author Information
1. Department of General Medicine, JCHO Hokkaido Hospital, Sapporo, Japan. masshi@isis.ocn.ne.jp
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Late-onset;
Steroid therapy
- MeSH:
Antibodies, Antinuclear;
Biopsy;
Cyclosporine;
Diagnosis;
Dyspnea;
Edema;
Hemoptysis;
Hemorrhage*;
Humans;
Lupus Erythematosus, Systemic*;
Lupus Nephritis;
Methylprednisolone;
Middle Aged;
Prednisolone;
Protein-Losing Enteropathies*;
Vitiligo*
- From:The Ewha Medical Journal
2015;38(3):121-125
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 60-year-old man who had been diagnosed with protein-losing enteropathy (PLE) and vitiligo at age 51 years was admitted with dyspnea, hemoptysis, and lower-limb edema. On the basis of computed tomography findings, the cause of respiratory symptoms was thought to be diffuse alveolar hemorrhage (DAH). The final diagnosis of late-onset systemic lupus erythematosus (SLE) was established on the basis of renal biopsy examinations that revealed evidence of active SLE with lupus nephritis (World Health Organization, class V) and positive results for antinuclear antibody. DAH, as well as PLE and vitiligo were attributed to SLE. The patient was successfully treated with methylprednisolone and then prednisolone in combination with cyclosporin A. Because late-onset SLE is rare and patients tend to show atypical symptoms, close attention should be paid to the preceding symptoms.
