A Case of Primary Effusion Lymphoma in a Patient with Chronic Kidney Disease.
- Author:
Miyeon KIM
1
;
Sanghoon HAN
;
Jung Re YU
;
Woo Seong JEONG
;
Hyun Woo KIM
;
Jaechun LEE
;
Chang Lim HYUN
Author Information
1. Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea. btfulo@gmail.com
- Publication Type:Case Report
- Keywords:
Chemotherapy;
Diffuse large B cell lymphoma;
Primary effusion lymphoma
- MeSH:
Abdomen;
Antibodies, Monoclonal, Murine-Derived;
B-Lymphocytes;
Doxorubicin;
Dyspnea;
Exudates and Transudates;
Female;
Herpesvirus 8, Human;
HIV;
Humans;
Liver Diseases;
Lymph Nodes;
Lymphoma;
Lymphoma, Primary Effusion;
Middle Aged;
Pleural Effusion;
Renal Insufficiency, Chronic;
Serologic Tests;
Thorax;
Vincristine;
Rituximab
- From:Korean Journal of Medicine
2012;83(3):385-389
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Human herpes virus-8 (HHV-8)-negative primary effusion lymphoma (PEL) is frequently observed in patients with chronic liver disease. We describe herein a case of PEL in a patient with chronic kidney disease. A 59-year-old woman presented with dyspnea. The patient had a history of uncontrolled pleural effusion. The pleural effusion revealed a malignant cell-dominant exudate. Serological tests were negative for human immunodeficiency virus (HIV). Initial chest and abdomen computed tomography showed bilateral pleural effusion; however, no evidence of a tumor mass or lymph node enlargement was found. A malignant lymphoma of diffuse large B-cell type was confirmed by pleural fluid cytology. Immunohistochemical staining of malignant cells was negative for HHV-8. She was treated with rituximab and CHOP (cyclophosphamide, adriamycin, vincristine, prednisolone) chemotherapy. We report a case of PEL in a patient with chronic kidney disease that may be a plausible predisposing factor for HHV-8-negative PEL.
