M-VAC Combination Chemotherapy in Advanced Bladder Cancer.
- Author:
Kyung Seob LEE
1
;
Chun Il KIM
;
Sung Choon LEE
Author Information
1. Keimyung University, School of Medicine, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
bladder cancer;
chemotherapy;
M-VAC
- MeSH:
Doxorubicin;
Drug Therapy;
Drug Therapy, Combination*;
Humans;
Prognosis;
Recurrence;
Urinary Bladder Neoplasms*;
Urinary Bladder*
- From:Korean Journal of Urology
1987;28(1):74-78
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Patients with advanced carcinoma of the bladder that relapses or persists after conventional therapy have a poor prognosis. The management of the patient with recurrent local or disseminated bladder cancer presents a difficult clinical problem. In l985, Sternberg et al reported 7l% significant tumor regression and 50% complete clinical remission with M-VAC(Methotrexate, Vinblastin, Adriamycin and Cisplatin) combination chemotherapy for treatment of advanced bladder carcinoma Herein, we report 4 cases of M-VAC combination chemotherapy in far advanced bladder carcinoma with had measurable metastatic lesions enough to evaluate the objective response of chemotherapy.
