Exfoliative Dermatitis and Toxic Hepatitis Associated with Occupational Exposure to Trichloroethylene.
- Author:
Hong Jae CHAE
1
;
Seong Kwan LEE
;
Kang Jin LEE
;
Jong Youl KIM
;
Seung Chul LEE
;
Dong Hyeon SHIN
;
Jai Dong MOON
Author Information
1. Department of Occupational and Environmental Medicine, Chonnam National University Hospital, Korea. ajdmoon@chollian.net
- Publication Type:Case Report
- Keywords:
Trichloroethylene;
Hepatitis;
Exfoliative dermatitis
- MeSH:
Adult;
Chills;
Cholestasis;
Dermatitis;
Dermatitis, Exfoliative*;
Drug-Induced Liver Injury*;
Exanthema;
Fever;
Hepatitis;
Humans;
Hypersensitivity;
Liver;
Male;
Occupational Exposure*;
Patch Tests;
Pruritus;
Trichloroethylene*
- From:Korean Journal of Occupational and Environmental Medicine
2003;15(1):111-117
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 28-year-old male began working as a degreaser. The solvent used in the degreasing operation was trichloroethylene. Over the next month the man experienced fever, chills, and an erythematous skin rash and itching. At that time he had a marked elevation in his liver enzyme, with cholestasis. Over the next few days the rash persisted then peeled. There was an elevation of Ig E, and a positive patch test reaction to trichloroethylene. His dermatitis and hepatitis were considered to be mediated by a hypersensitivity mechanism.
