Cardiac arrest following reversal of muscle relaxation by pyridostigmine: A case report.
- Author:
Jun Young JO
1
;
Jung Min YI
;
Yoon Kyung LEE
;
Seung Woo KU
;
Pyung Hwan PARK
Author Information
1. Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. swkoo@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Cardiac arrest;
Coronary spasm;
Pyridostigmine;
Reversal of neuromuscular block
- MeSH:
Anesthesia, General;
Cholinergic Agents;
Cholinergic Antagonists;
Cholinesterase Inhibitors;
Coronary Vasospasm;
Heart Arrest*;
Humans;
Male;
Middle Aged;
Muscle Relaxation*;
Neuromuscular Blockade;
Neuromuscular Nondepolarizing Agents;
Pyridostigmine Bromide*
- From:Anesthesia and Pain Medicine
2014;9(3):205-208
- CountryRepublic of Korea
- Language:English
-
Abstract:
The anticholinesterase pyridostigmine is usually used as a reversal agent of non-depolarizing muscle relaxants in general anesthesia. Most adverse muscarinic effects of anticholinesterases are controlled by anticholinergics; however, there is still a potential for fatal cardiac complications. We report a case of cardiac arrest associated with coronary vasospasm that developed during emergence from general anesthesia in a 61-year-old male patient undergoing uvulopalatopharyngoplasty with preoperatively undiagnosed coronary vasospastic angina. Anticholinesterases should be administered with caution for neuromuscular blockade reversal, especially in patients with coronary vasospastic angina.
