Necrobiotic Xanthogranuloma with Monoclonal Gammopathy.
- Author:
Hyun Kyu KIM
1
;
In Kwon YEO
;
Dong Ha KIM
;
Kui Young PARK
;
Kapsok LI
;
Seong Jun SEO
;
Chang Kwun HONG
;
Kye Yong SONG
Author Information
1. Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea. ksli0209@medimail.co.kr
- Publication Type:Case Report
- Keywords:
Monoclonal gammaopathy;
Necrobiotic xanthogranuloma
- MeSH:
Humans;
Hyalin;
Hypertension;
Multiple Myeloma;
Necrobiotic Disorders;
Necrobiotic Xanthogranuloma;
Necrosis;
Paraproteinemias
- From:Korean Journal of Dermatology
2012;50(2):152-155
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Necrobiotic xanthogranuloma (NXG) is a rare, progressive, histiocytic disease characterized by destructive cutaneous lesions, a close association with paraproteinemia, multiple myeloma, hypertension, and multiple extracutaneous manifestations. Multiple indurated yellow-red plaques or nodules are commonly present in this disorder. The pathogenesis of NXG is poorly understood. Histopathologically, NXG features with hyaline necrosis or necrobiosis are present. We describe a patient with typical cutaneous and histologic findings of NXG with an associated monoclonal gammopathy.
