Anticoccidial effects of Galla rhois extract on Eimeria tenella-infected chicken.
10.5625/lar.2012.28.3.193
- Author:
Hyun A LEE
1
;
Sunhwa HONG
;
Yung Ho CHUNG
;
Ki Duk SONG
;
Okjin KIM
Author Information
1. Korean Medicine (KM)-Based Herbal Drug Research Group, Korea Institute of Oriental Medicine, Dajeon, Korea.
- Publication Type:Original Article
- Keywords:
Anticoccidial activity;
coccidiosis;
eimeria;
eimeria tenella;
galla rhois
- MeSH:
Animals;
Body Weight;
Chickens;
Coccidiosis;
Diet;
Eimeria;
Eimeria tenella;
Feces;
Oocysts;
Polymerase Chain Reaction
- From:Laboratory Animal Research
2012;28(3):193-197
- CountryRepublic of Korea
- Language:English
-
Abstract:
Anticoccidial effects of Galla rhois (GR) extract were evaluated in chickens after oral infection with Eimeria tenella. This study was performed using 3-day-old chickens (n=30). The animals were divided into 3 groups as follows: GR 0.5%/infected (n=10), untreated/infected (n=10), and non-infected control (n=10). The chickens were fed a standard diet supplemented with or without GR for 1 week before infection with E. tenella (10,000 sporulated oocysts per chicken). The effects of GR on E. tenella infection were assessed by 2 parameters, number of fecal oocysts and body weight gain, and the results of the polymerase chain reaction (PCR). The GR-fed chickens produced significantly lower number of fecal oocysts (P<0.05) than the E. tenella-infected chickens who were fed the standard diet. In addition, GR-based diet improved the loss of body weight caused by E. tenella infection. Positive findings of PCR were identified by distinct bands in the samples of E. tenella-inoculated chickens. However, PCR analysis revealed no E. tenella oocysts in the feces of GR-fed chickens. Our data showed that GR extracts had remarkable anticoccidial activities against E. tenella. This finding might have implications for the development of novel anticoccidial drugs.
