Two Cases of ABO Discrepancy due to Hypogammaglobulinemia.
- Author:
In Bum SUH
1
;
Eun Ah CHANG
;
Hyo Jung KIM
;
Chang Don KANG
;
Sung Joon LEE
;
Tae Sik KIM
;
Sook Won RYU
;
Chae Seung LIM
;
Kap No LEE
;
Kyung Ran MA
Author Information
1. Department of Laboratory Medicine, Kangwon National University College of Medicine, Chuncheon, Korea.
- Publication Type:Original Article
- Keywords:
ABO discrepancy;
Hypogammaglobulinemia;
B transferase activity;
ABO genotype
- MeSH:
Abscess;
Adsorption;
Agammaglobulinemia*;
Carcinoma, Hepatocellular;
Electrophoresis;
Female;
Genotype;
Humans;
Immunoglobulin A;
Immunoglobulins;
Polymerase Chain Reaction;
Saliva;
Transferases;
Urinary Bladder
- From:Korean Journal of Blood Transfusion
2003;14(2):240-245
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Two cases of ABO discrepancy were observed in thirty-year old woman with gall bladder abscess and fifty-five-year old woman with hepatocellular carcinoma. Their red cells were typed as group O and their serum had only anti-A antibody. Absence of A and B antigens on their RBCs were confirmed by adsorption elution test and saliva test. The B transferase activities were not demonstrated in their serum. Their ABO genotypes were O/O by sequence specific polymerase chain reaction. Their serum protein electrophoresis showed hypogammaglobulinemia pattern, and immunoglobulin levels (IgG, IgA, IgM) were decreased (39 mg/dL, 46 mg/dL, <5 mg/dL and 63 mg/dL, 65 mg/dL, 12 mg/dL, respectively).
