Comparison of Gadomer-17 and Gd-DTPA in image quality of contrast-enhanced MR angiographies using flow phantom model.
10.3349/ymj.1999.40.5.413
- Author:
Byung June JO
1
;
Tae Sub CHUNG
;
Myung Sik LEE
;
Jin Yang JOO
;
Wolfgang EBERT
;
Hanns Joachim WEINMANN
;
Daisy CHIEN
;
Gerhard LAUB
Author Information
1. Department of Diagnostic Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea. tschung@yumc.yonsei.ac.kr
- Publication Type:Original Article ; Comparative Study
- Keywords:
Magnetic resonance imaging;
carotid flow phantom;
magnetic resonance angiography;
Gadolinium
- MeSH:
Comparative Study;
Contrast Media*/administration & dosage;
Dose-Response Relationship, Drug;
Gadolinium DTPA/diagnostic use*;
Human;
Magnetic Resonance Angiography*
- From:Yonsei Medical Journal
1999;40(5):413-419
- CountryRepublic of Korea
- Language:English
-
Abstract:
The purpose of this study was to compare the image quality of 3D-TOF MR angiography (MRA) using Gadomer-17 with that using Gd-DTPA in a flow phantom model, and to present preliminary data about the proper dose concentration of Gadomer-17. In the visual analysis of vessel conspicuity, we compared the quality of pre- and post-contrast MIP images. For quantitative analysis, the signal intensities were measured in the axial base 3D-TOF images, and then the relative contrast enhancement was calculated. The results of our studies were that: 1. Maximal signal intensities were obtained at 1 mmol/L of Gadomer-17 and 4 mmol/L of Gd-DTPA. 2. Flow-related signal loss was decreased by Gd-DTPA proportional to the concentration, but Gadomer-17 did not show such a dose accumulative effect. In conclusion, after comparing the results of Gd-DTPA, it was clear that improved MRA images and higher signal intensities of vessels were obtained when lower concentrations of Gadomer-17 were used.
