A case with intrahepatic double cancer: hepatocellular carcinoma and cholangiocarcinoma associated with multiple von Meyenburg complexes.
10.3349/ymj.1999.40.5.506
- Author:
Youn Wha KIM
1
;
Yong Koo PARK
;
Jae Hoon PARK
;
Juhie LEE
;
Sang Mok LEE
;
Sung Wha HONG
;
Moon Ho YANG
Author Information
1. Department of Pathology, College of Medicine, Kyung Hee University, Seoul, Korea. kimyw@nms.kyunghee.ac.kr
- Publication Type:Case Report
- Keywords:
Double cancer;
hepatocellular carcinoma;
cholangiocarcinoma;
von Meyenburg complex
- MeSH:
Aged;
Bile Ducts, Intrahepatic/abnormalities*;
Carcinoma, Hepatocellular/pathology*;
Carcinoma, Hepatocellular/etiology;
Case Report;
Cholangiocarcinoma/pathology*;
Cholangiocarcinoma/etiology;
HumanLiver Neoplasms/pathology*;
Liver Neoplasms/etiology;
Male;
Neoplasms, Multiple Primary/pathology*;
Neoplasms, Multiple Primary/etiology
- From:Yonsei Medical Journal
1999;40(5):506-509
- CountryRepublic of Korea
- Language:English
-
Abstract:
Combined hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) is sometimes found in resected livers, however, cases with double cancer of HCC and CC are very rare. As well, the rarity of CC arising in von Meyenburg complexes (VMCs) is appreciated. We report the case of a 74-year-old man found to have intrahepatic double cancer composed of well-differentiated HCC and CC which exhibited a histologic progression from VMCs to adenomatous lesions and CC. To our knowledge, this is the first case report published in the literature of a double HCC and CC associated with multiple VMCs. The pathogenesis and previous associated reports of these lesions are discussed.
