A Case of Pancreatic Cancer with Markedly Elevated Serum Immunoglobulin G4.
10.15279/kpba.2015.20.2.78
- Author:
Young Seok KWON
1
;
Sung Hoon MOON
;
Ho Suk KANG
;
Hyun LIM
;
Nan Young CHOI
;
Soon Young KIM
;
Dong Hun KANG
;
Jong Hyeok KIM
Author Information
1. Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea. endomoon@naver.com
- Publication Type:Case Report
- Keywords:
Serum immunoglobulin G4;
Pancreatic cancer;
Autoimmune pancreatitis
- MeSH:
Diagnosis, Differential;
Humans;
Immunoglobulin G;
Immunoglobulins*;
Pancreatic Neoplasms*;
Pancreatitis
- From:Korean Journal of Pancreas and Biliary Tract
2015;20(2):78-82
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Differential diagnosis between autoimmune pancreatitis (AIP) and pancreatic cancer is often difficult due to similar clinical manifestations and radiological findings. Serum immunoglobulin G4 (IgG4) is a marker to differentiate AIP from pancreatic cancer. Although serum IgG4 can be elevated in 10% of patients with pancreatic cancer, most of serum IgG4 elevation in pancreatic cancer is limited within two times of upper normal limit. Herein, we report a case of pancreatic cancer with markedly elevated serum IgG4 over six times of upper normal limit that needed steroid trial to differentiate from AIP.
