A Case of Combined Congenital Hepatic Fibrosis and Biliary Hamartoma Presented with Recurrent Acute Cholangitis.
10.15279/kpba.2015.20.2.105
- Author:
Ki Bae KIM
1
;
Myoung Jin JI
;
Ji Youl YANG
;
Joung Ho HAN
;
Hee Bok CHAE
;
Seon Mee PARK
;
Min Ho KANG
;
Rohyun SUNG
;
Sei Jin YOUN
Author Information
1. Department of Internal Medicine, College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea. smpark@chungbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Biliary hamartoma;
Congenital hepatic fibrosis;
Recurrent acute cholangitis
- MeSH:
Aged;
Anti-Bacterial Agents;
Biopsy;
Cholangiopancreatography, Endoscopic Retrograde;
Cholangitis*;
Cholecystectomy;
Cholecystitis, Acute;
Diagnosis;
Fibrosis*;
Follow-Up Studies;
Hamartoma*;
Humans;
Liver;
Pathology;
Shock, Septic;
Tomography, X-Ray Computed
- From:Korean Journal of Pancreas and Biliary Tract
2015;20(2):105-110
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Biliary hamartoma and congenital hepatic fibrosis belong to fibrocystic disorders originating from ductal plate malformation. A 66-year-old man who had incidentally been diagnosed with biliary hamartoma two years ago presented to us with recurrent acute cholangitis. In the first episode, he had presented with septic shock and was treated with endoscopic retrograde cholangiopancreatography (ERCP) and cholecystectomy under the diagnosis of acute cholecystitis and cholangitis. However, during a two-month follow-up period, the patient experienced four episodes of acute cholangitis. Because he showed normal ERCP, and biliary hamartoma is usually asymptomatic, a liver biopsy was performed. Pathology revealed combined features of biliary hamartoma and congenital hepatic fibrosis, characterized as periportal fibrosis and intrahepatic ductular dysplasia. During follow-up for the last six months, he had experienced two episodes of acute cholangitis and was treated with antibiotics. A follow-up abdominal CT scan revealed aggravated hepatosplenomegaly compared to that of two years ago. We report a case of combined congenital hepatic fibrosis and biliary hamartoma and a literature review.
