A Case of Acral Persistent Papular Mucinosis in Patient with HIV Infection.
- Author:
Jae Eun CHOI
1
;
Ji Woong KIM
;
Hyun Min CHO
;
Hyo Hyun AHN
;
Young Chul KYE
;
Soo Nam KIM
Author Information
1. Department of Dermatology, College of Medicine, Korea University, Seoul, Korea. dermp@shinbiro.com
- Publication Type:Case Report
- Keywords:
Acquired immunodeficiency syndrome;
Acral persistent papular mucinosis;
Cutaneous mucinosis;
Human immunodeficiency virus;
Lichen myxedematosus
- MeSH:
Acquired Immunodeficiency Syndrome;
Adult;
Antiretroviral Therapy, Highly Active;
Dermis;
Forearm;
Hand;
HIV Infections*;
HIV*;
Humans;
Male;
Mucins;
Scleromyxedema*;
Wrist
- From:Korean Journal of Dermatology
2007;45(9):951-955
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acral persistent papular mucinosis (APPM) is a rare subtype of localized lichen myxedematosus, which involves only the extensor surfaces of the hands, wrists and the distal part of forearms. Some subtypes of lichen myxedematosus including APPM have been reported with increased frequency in a patient with human immunodeficiency virus (HIV) infection. We describe a 31 year-old male patient with an HIV infection who presented with discrete, flesh-colored papules on the extensor surfaces of the wrists and the distal part of the forearms. Histopathologic findings revealed focal deposition of mucin in papillary and mid dermis that spared a small grenz zone. The lesions showed spontaneous regression after starting highly active antiretroviral therapy (HAART). We report a rare case of APPM in a patient with HIV infection which showed spontaneous regression with HAART, suggesting that APPM may represent one of the cutaneous markers of HIV infection.
