A case of typhoid fever with manifestations of acute hepatitis.
- Author:
Jong Woon HWANG
1
;
Ho Myung LEE
;
Dae Hee HAN
;
Ji Eun OH
;
Jung Su HA
;
Dae Hyeon CHO
;
Sang Goon SHIM
Author Information
1. Department of Internal Medicine, Masan Samsung Hospital Sungkyunkwan University School of Medicine, Masan, Korea. sgshim@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Typhoid fever;
Salmonella typhi;
Hepatitis
- MeSH:
Bilirubin;
Biopsy;
Ceftriaxone;
Fever;
Hepatitis;
Hepatocytes;
Humans;
Jaundice;
Liver;
Lymphatic Diseases;
Middle Aged;
Necrosis;
Salmonella typhi;
Splenomegaly;
Typhoid Fever
- From:Korean Journal of Medicine
2008;75(1):77-81
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Typhoid fever is a febrile illness with a variety of systemic manifestations; however, icteric typhoid hepatitis, mimicking the clinical features of acute hepatitis, is very uncommon. A 45-year-old man was admitted to the hospital for evaluation of fever, dark-colored urine, and jaundice. On admission, the total bilirubin was 4.3 mg/dL, and the AST and ALT were 468 and 319 IU/L, respectively. Salmonella typhi was identified by blood culture. A liver biopsy revealed some mononuclear cell infiltrations without hepatocyte necrosis or typhoid nodules. CT scan findings showed splenomegaly and mesenteric lymphadenopathy. With the administration of ceftriaxone, he became afebrile and showed improvement in the jaundice, with normalization of AST and ALT.
