A Brief Report on the Myocardial Damage Evaluated by Creatine Kinase MB Isoenzyme in Valvular Heart Disease.
10.4097/kjae.1985.18.3.263
- Author:
Pyung Hwan PARK
1
;
Byung Tae SEO
Author Information
1. Department of Anesthesiology Guro Hospital, Korea University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Anesthesia;
Creatine Kinase*;
Creatine*;
Heart;
Heart Valve Diseases*;
Humans
- From:Korean Journal of Anesthesiology
1985;18(3):263-268
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
During a 3 month period in 1984, 12 patients undergoing scheduled valvular replacement were Studied by CK and CK-MB isoenzyme to evaluate the myocardial damage during open heart operation. Total creatine kinase value was 58.3+/-25.6 u/L at control, 59.8+/-23.5 u/L at prebypass period, 85.5+/-49.6 U/L at during bypass period, 20.2+/-87.6 at postbypass period respectively. It began to rise in prebypass period and showed higtest level in postbypass period. CK-MB value was low in most cases below 20 U/L but in 2 patients postbypass period showed high level which above 40U/L. Initial isoenzyme activity was detected in 2 patients prior to anesthesia, in 2patients prior to bypass, in 5 patients during bypass, and in all others after termination of bypass. Considering above data we concluded that anesthetic management during prebypass period and myocardial preservation during bypass period required more proper and aggressive management despite of good operation results.
